Wernicke’s Encephalopathy

نویسنده

  • Nirankar Singh Neki
چکیده

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Background: ″Wernicke’s Korsakoff″ syndrome is the most important complication of severe thiamine deficiency. The term refers to two different syndromes, each representing a different stage of the disease. Wernicke’s encephalopathy (WE) is an acute syndrome requiring emergent treatment to prevent death and neurologic morbidity. Korsakoff syndrome (KS) refers to a chronic neurologic condition th...

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The nucleus basalis (Ch4) in the alcoholic Wernicke-KorsakoV syndrome: reduced cell number in both amnesic and non-amnesic patients

Background—The cholinergic nucleus basalis (Ch4) is an exclusive site of neurofibrillary degeneration in alcoholic patients with Wernicke’s encephalopathy. Aim—To test the hypothesis that the loss of Ch4 neurons contributes to thememory disorder, KorsakoV’s psychosis, commonly seen in Wernicke’s encephalopathy. Methods—Magnocellular basal forebrain neurons were quantified in alcoholic patients ...

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Wernicke’s encephalopathy is an acute neurological syndrome due to thiamine deficiency. Though classically described in relation to chronic malnutrition associated with alcoholism, it can also be precipitated in nonalcoholics due to various causes like gastrointestinal surgeries, recurrent vomiting, peptic ulcer disease, cancer chemotherapy and peritoneal or hemodialysis [1]. As the classical t...

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rologic disorder that is caused by a nutritional deficiency of thiamine. This malady is characterized by a classic triad of clinical symptoms that include gait ataxia, ophthalmoplegia and changes in consciousness. The anatomical sites that are most frequently involved in Wernicke’s encephalopathy are the mamillary bodies, periaqueductal regions, bilateral medial thalami, third ventricular walls...

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Wernicke’s encephalopathy, an acute neuropsychiatric syndrome caused by thiamine (vitamin B 1 ) deficiency, is associated with serious clinical disease and can be fatal. It has rarely been reported in infants and children. We report a case of a 3-year-old girl with Wernicke’s encephalopathy. The patient’s diet had been severely unbalanced since the age of 2 years, and for about a month prior to...

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تاریخ انتشار 2015